Linked Life Data

391579

Source:http://linkedlifedata.com/resource/pubmed/id/391579

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1980-3-27
pubmed:abstractText
Migratory patterns into lymph nodes of labeled spleen lymphocytes, injected intravenously, showed considerable differences according to the genetic identity or disparity of donor and recipient mice. The use of mice carrying different H-2 haplotypes in the same B 10 background, or, conversely, the same H-2b haplotype in different backgrounds, showed that no homing was observed in the case of complete disparity at the H-2 complex, contrasting with optimal homing in the case of H-2 identity. Homing was not influenced by disparity at the genetic background. Irradiation of recipient mice did not change the results and suggested that no immunological host-vs.-graft reaction was involved in the H-2 restriction observed. The use of donor-recipient pairs carrying recombinant H-2 haplotypes showed that a single H-2 K and/or H-2 D identity allowed almost optimal homing. The results indirectly suggested that an immunological graft-vs.-host reaction was not involved in the phenomenon but rather a positive recognition of H-2 K or H-2 D identity between donor and recipient cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0014-2980
pubmed:author
pubmed:issnType
Print
pubmed:volume
9
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
808-14
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
H-2 restriction for lymphocyte homing into lymph nodes.
pubmed:publicationType
Journal Article