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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1986-7-25
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pubmed:abstractText |
The steroid (methylprednisolone) sensitivity of chronic uraemic and renal transplant patients was examined on the basis of the extent of inhibition of the antibody-dependent cellular cytotoxicity (ADCC) reaction, and via the effect on the ADCC capacity test (ADCC-C). Individuals with an inhibition of 30% or more were classified as steroid-sensitive. Immunopharmacological tests and the clinical picture showed 67%, 12 of the 18 renal transplant patients to be steroid-sensitive. In 92% of the cases the transplanted kidney was functioning well one year or more postoperatively. In 5 of the 6 steroid-resistant patients rejection necessitated removal of the transplanted kidney. The method is simple to perform and gives reproducible results, and appears suitable for application in clinical practice.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0017-6559
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225-32
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3915294-Adolescent,
pubmed-meshheading:3915294-Adult,
pubmed-meshheading:3915294-Antibody-Dependent Cell Cytotoxicity,
pubmed-meshheading:3915294-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:3915294-Drug Resistance,
pubmed-meshheading:3915294-Graft Survival,
pubmed-meshheading:3915294-Humans,
pubmed-meshheading:3915294-Kidney Transplantation,
pubmed-meshheading:3915294-Lymphocytes,
pubmed-meshheading:3915294-Methylprednisolone,
pubmed-meshheading:3915294-Middle Aged,
pubmed-meshheading:3915294-Renal Dialysis,
pubmed-meshheading:3915294-Uremia
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pubmed:year |
1985
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pubmed:articleTitle |
Steroid sensitivity of chronic uraemic and renal transplant patients measured by the antibody dependent cellular cytotoxicity reaction.
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pubmed:publicationType |
Journal Article
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