Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1986-4-10
pubmed:abstractText
Clinical studies of topical acyclovir therapy in recurrent HSV episodes are reviewed. Efficacy is maximised by early patient initiated treatment at the onset of prodromal symptoms. Acyclovir cream is clearly superior to acyclovir ointment in treating recurrent genital and labial herpes where the antiviral and clinical benefits are comparable with those produced by short duration oral acyclovir therapy. Acyclovir cream is well tolerated and adverse events remain uncommon whilst efficacy persists even after repeated use in successive recurrent episodes. Topical therapy does not influence the natural history of recurrent HSV infections. For patients with less frequent recurrent HSV episodes involving localised and accessible sites topical acyclovir cream may be preferred to the equally effective but more expensive oral acyclovir.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-8878
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
58-62
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Topical acyclovir in the treatment of recurrent herpes simplex virus infections.
pubmed:publicationType
Journal Article, Clinical Trial