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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1986-3-11
|
| pubmed:abstractText |
To determine whether hyperaminoacidaemia may modify insulin-mediated glucose disposal, normal subjects were studied with the euglycaemic glucose-clamp technique, with or without an amino acid infusion, at a rate sufficient to duplicate the plasma concentration of most amino acids. Steady-state glucose infusion rates to maintain euglycaemia were 36% lower during hyperaminoacidaemia (7.3 +/- 1.0 versus 11.4 +/- 0.8 mg X kg-1 X min-1, p less than 0.01) at comparable insulin concentrations (92 +/- 6 versus 93 +/- 7 mU/l respectively). Thus, under conditions of hyperinsulinaemia, amino acids could compete with glucose as metabolic fuels.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0012-186X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
28
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
870-2
|
| pubmed:dateRevised |
2011-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:3910497-Adult,
pubmed-meshheading:3910497-Amino Acids,
pubmed-meshheading:3910497-Female,
pubmed-meshheading:3910497-Glucagon,
pubmed-meshheading:3910497-Glucose,
pubmed-meshheading:3910497-Humans,
pubmed-meshheading:3910497-Insulin,
pubmed-meshheading:3910497-Male,
pubmed-meshheading:3910497-Middle Aged
|
| pubmed:year |
1985
|
| pubmed:articleTitle |
Hyperaminoacidaemia reduces insulin-mediated glucose disposal in healthy man.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|