Linked Life Data

3909887

Source:http://linkedlifedata.com/resource/pubmed/id/3909887

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1986-2-11
pubmed:abstractText
The intermediate filament gene vimentin exists in a single copy in the chick haploid genome. However, it exhibits the curious property of producing at least three functional vimentin mRNA transcripts in vivo through the differential utilization of multiple polyadenylylation sites. According to one group in erythroid cells there may be a tissue-specific utilization of one of these poly A addition sites. The chicken and hamster vimentin genes exhibit remarkable nucleotide sequence homology both within coding and 3'-noncoding regions (82%). This nucleotide homology extends both to the size and juxtaposition of exons. With the noted exception of valine, even the frequency of codons utilized is strongly conserved across the widely different species. Of course, this strong homology at the DNA level extends to an amino acid homology of 92% between vimentins and 65% between related proteins in the same species.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0077-8923
pubmed:author
pubmed:issnType
Print
pubmed:volume
455
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
79-94
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
The chicken vimentin gene: aspects of organization and transcription during myogenesis.
pubmed:publicationType
Journal Article, Comparative Study, Review