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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1986-2-7
|
| pubmed:abstractText |
Antimineralocorticoid drugs are widely prescribed as hypertensive agents, with an efficacy comparable to other drugs (thiazide diuretics, beta-blockers), especially in low-renin hypertension. However they require a prolonged lag-time (several weeks) in order to obtain maximal hypotensive effect. There is no hypokalemia and its possible cardiac and metabolic consequences. They are sometimes responsible for dose-dependent sexual side effect. Knowing the pathophysiology of these effects as well as the precise renal and extra-renal mechanism of action of antimineralocorticoids should lead to the discovery of new specific, efficient and safe compounds for which there is need in the management of hypertension.
|
| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0250-4960
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
145-6
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading | |
| pubmed:year |
1985
|
| pubmed:articleTitle |
[Aldosterone antagonists: hypotensive and natriuretic drugs].
|
| pubmed:publicationType |
Journal Article,
English Abstract,
Review
|