Linked Life Data

3906878

Source:http://linkedlifedata.com/resource/pubmed/id/3906878

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
41
pubmed:dateCreated
1986-1-21
pubmed:abstractText
15 years' experience in large scale search for immune complexes has revealed abnormally high levels of such complexes in a wide variety of inflammatory diseases. The original hope of using immune complex detection for improved diagnosis has somewhat waned, but a new impetus in complex detection has been given by the increasing precision with which we can detect the antigens within the complexes: such techniques as gel electrophoresis and Western blotting will, once made easier for the routine clinical laboratory, foster further search for pathogenetic immune complexes. In addition, study of immune complex-receptor systems such as complement, macrophages and lymphocytes helps to explain the way complexes are handled by these components of the immune system and raises the question whether the difficulty of eliminating pathogenic antigens of bacterial, viral or autoimmune nature through immune complex formation in fact is not a defect in antibody formation but rather a defect in clearing the opsonized antigen from circulation. Investigators who read English are referred to a similar text by the same author (Immunology Today 6, 80-82 [1985].
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0036-7672
pubmed:author
pubmed:issnType
Print
pubmed:day
12
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1414-22
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Determination of circulating immune complexes and their significance for diagnosis and therapy].
pubmed:publicationType
Journal Article, English Abstract