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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1980-2-26
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pubmed:abstractText |
The sequence of two new IS2 alleles with promoter activity (IS2-43 and IS2-44) is reported. The alleles are identical and are formed by a 17 bp tandem duplication in an AT-rich region of IS2. This created a new RNA polymerase binding site. A mutation was found that increased the frequency of formation of these 17 bp duplications but not of another class of duplications, the "mini-insertions". This suggested that the mechanisms of formation of the two classes of duplications are different.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0026-8925
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
175
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
53-6
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pubmed:dateRevised |
2002-11-1
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pubmed:meshHeading |
pubmed-meshheading:390307-Alleles,
pubmed-meshheading:390307-Base Sequence,
pubmed-meshheading:390307-DNA, Bacterial,
pubmed-meshheading:390307-DNA Transposable Elements,
pubmed-meshheading:390307-DNA-Directed RNA Polymerases,
pubmed-meshheading:390307-Escherichia coli,
pubmed-meshheading:390307-Mutation,
pubmed-meshheading:390307-Nucleic Acid Hybridization
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pubmed:year |
1979
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pubmed:articleTitle |
IS2-43 and IS2-44: new alleles of the insertion sequence IS2 which have promoter activity.
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pubmed:publicationType |
Journal Article
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