Linked Life Data

3902662

Source:http://linkedlifedata.com/resource/pubmed/id/3902662

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1985-11-25
pubmed:abstractText
MLW1, an antigen preparation from Mycobacterium leprae previously shown to have a high content of M. leprae antigen No. 7 (ML7), was found to contain the typical cell wall constituents arabinose, galactose and mannose. The fatty acid composition of MLW1 was largely comparable to that of undisrupted cells. The capacity of MLW1 to stimulate lymphocytes was further studied. Good correlation was obtained between the in vitro lymphocyte responses to MLW1 and human-derived M. leprae, indicating similar specificity of the two antigen preparations in this test. The stimulatory activity of MLW1 was not significantly influenced by batch to batch variations, was well-preserved during storage and most of it was heat-stable. Attempts to remove the ML7 antigen indicate that this component plays a dominant role in inducing in vitro lymphocyte stimulation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0020-5915
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
269-76
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Further characterization including preliminary chemical analysis of antigen MLW1 from Mycobacterium leprae.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't