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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1980-2-15
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pubmed:abstractText |
A unique and characteristic bacteriocine-like inhibitor elaborated by M-type 4, T-pattern 4, group-A streptococci was isolated and partially purified. This inhibitor was found to be produced optimally in Todd-Hewitt broth; after extraction and concentration, was shown to be protein in nature, and to have a m.w. of c. 8000. It was extremely heat stable and acid tolerant, but was quickly inactivated in alkaline conditions. It could be demonstrated in cell-bound form, but 99.5% was found in culture supernates. It was specifically adsorbed by viable sensitive cells, and its mode of action was bacteristatic.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0022-2615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
413-27
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:390151-Antigens, Bacterial,
pubmed-meshheading:390151-Bacteriocins,
pubmed-meshheading:390151-Hot Temperature,
pubmed-meshheading:390151-Molecular Weight,
pubmed-meshheading:390151-Peptide Hydrolases,
pubmed-meshheading:390151-Staphylococcus,
pubmed-meshheading:390151-Streptococcus pyogenes
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pubmed:year |
1979
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pubmed:articleTitle |
Production of a bacteriocine-like substance by group-A streptococci of M-type 4 and T-pattern 4.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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