Linked Life Data

3900924

Source:http://linkedlifedata.com/resource/pubmed/id/3900924

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1985-11-6
pubmed:abstractText
During the last thirty years several in vitro techniques have been developed to predict sensitivity of individual tumours. When the results of these techniques were correlated with the clinical response in larger groups of patients, the accuracy for predicting resistance was greater than for predicting sensitivity. Amongst the culture techniques the colony-forming assays have received much attention. Research with tumour cell lines and the sound biological basis do support this preference on other techniques. Studies on these assays have come from several independent laboratories, who report comparable results. Improvement of the culture technique and more insight into the in vitro pharmacology is needed, before application on wider scale is justified. Colony-forming culture techniques have not only been propagated for individualized chemotherapy, but also for drug screening. New antitumour agents and analogous can be screened in a short time for their sensitivity in many histologic tumour types.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0167-6555
pubmed:author
pubmed:issnType
Print
pubmed:day
23
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
125-33
pubmed:dateRevised
2008-2-25
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Predictive testing in cancer chemotherapy. II. In vitro.
pubmed:publicationType
Journal Article, Review