Linked Life Data

3899777

Source:http://linkedlifedata.com/resource/pubmed/id/3899777

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1985-10-29
pubmed:abstractText
We have used immunofluorescent staining of sea urchin embryos to study how histone H1 alpha is distributed among progeny cells formed after the cessation of its synthesis. Our results are consistent with H1 alpha being distributed to both daughter cells at mitosis, resulting in it being most concentrated in cells that stop dividing shortly after H1 alpha synthesis ends, while cells that continue to divide dilute their H1 alpha content in proportion to the number of cell divisions. This rules out our earlier suggestion that H1 alpha becomes segregated in dividing cells. In addition, our results show that most dividing cells of the 3-day embryo contain predominantly H1 beta and H1 gamma. Since these subtypes are known not to undergo phosphorylation, this finding has implications regarding the roles of H1 phosphorylation in the cell cycle.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0012-1606
pubmed:author
pubmed:issnType
Print
pubmed:volume
111
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
530-3
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Distribution of histone H1 alpha among cells of the sea urchin embryo.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't