rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1985-10-21
|
pubmed:abstractText |
We compared subconjunctivally administered ceftazidime and BMY 28142, two third-generation cephalosporins, to a regimen of gentamicin and cefazolin for their ability to prevent experimental Pseudomonas postoperative endophthalmitis in rabbits. After extracapsular lens extraction, an inoculum of Pseudomonas was injected into the vitreous; one of the three antimicrobial regimens was then administered subconjunctivally. All 25 eyes treated with gentamicin and cefazolin become infected (P = 1). Two of 25 eyes treated with BMY 28142 became infected (P less than .001). None of the 25 eyes treated with ceftazidime became infected (P less than .001).
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0002-9394
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
100
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
404-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3898852-Animals,
pubmed-meshheading:3898852-Anti-Bacterial Agents,
pubmed-meshheading:3898852-Cefazolin,
pubmed-meshheading:3898852-Ceftazidime,
pubmed-meshheading:3898852-Cephalosporins,
pubmed-meshheading:3898852-Drug Combinations,
pubmed-meshheading:3898852-Drug Evaluation, Preclinical,
pubmed-meshheading:3898852-Eye Diseases,
pubmed-meshheading:3898852-Gentamicins,
pubmed-meshheading:3898852-Inflammation,
pubmed-meshheading:3898852-Postoperative Period,
pubmed-meshheading:3898852-Pseudomonas Infections,
pubmed-meshheading:3898852-Rabbits
|
pubmed:year |
1985
|
pubmed:articleTitle |
Multistrain comparison of three antimicrobial prophylaxis regimens in experimental postoperative Pseudomonas endophthalmitis.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|