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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8 Pt 2
|
pubmed:dateCreated |
1985-9-16
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pubmed:abstractText |
Treatment-emergent symptoms and behavioral changes were assessed during an 8-week double-blind study comparing molindone and thioridazine in 31 aggressive hospitalized children (ages 6-11). Molindone was found to be as effective as thioridazine in this sample. Adverse effects differed (nonsignificantly) for the two groups, with more sedation in the thioridazine-treated children. Clinical records from 6 adolescent inpatients treated with molindone were reviewed as a comparison group. Molindone is a relatively safe neuroleptic for child and adolescent inpatients because of its short half-life and minimal prolonged tissue accumulation. Additional studies on different child populations are necessary before the proper indications for molindone usage in the pediatric group can be established.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
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pubmed:issn |
0160-6689
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
20-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3894338-Adolescent,
pubmed-meshheading:3894338-Age Factors,
pubmed-meshheading:3894338-Aggression,
pubmed-meshheading:3894338-Child,
pubmed-meshheading:3894338-Child Behavior Disorders,
pubmed-meshheading:3894338-Clinical Trials as Topic,
pubmed-meshheading:3894338-Double-Blind Method,
pubmed-meshheading:3894338-Dystonia,
pubmed-meshheading:3894338-Half-Life,
pubmed-meshheading:3894338-Hospitalization,
pubmed-meshheading:3894338-Humans,
pubmed-meshheading:3894338-Indoles,
pubmed-meshheading:3894338-Male,
pubmed-meshheading:3894338-Molindone,
pubmed-meshheading:3894338-Placebos,
pubmed-meshheading:3894338-Psychiatric Status Rating Scales,
pubmed-meshheading:3894338-Sleep,
pubmed-meshheading:3894338-Thioridazine
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pubmed:year |
1985
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pubmed:articleTitle |
Molindone hydrochloride treatment of hospitalized children with conduct disorder.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial
|