rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
8
|
pubmed:dateCreated |
1985-9-6
|
pubmed:abstractText |
A double blind controlled trial has been conducted in 40 patients to compare the therapeutic effects of prednisolone metasulphobenzoate enemas with those of prednisolone-21-phosphate enemas. Both enemas brought about improvement in symptoms and sigmoidoscopic appearances in more than 70% of patients treated. The absorption of prednisolone from the metasulphobenzoate enema in three patients was less than from the 21-phosphate enema. In view of the low plasma prednisolone concentrations obtained, there are theoretical advantages in using a poorly absorbed enema to avoid the possibility of systemic steroid effects in patients requiring long term steroid treatment.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Aug
|
pubmed:issn |
0017-5749
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
26
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
822-4
|
pubmed:dateRevised |
2009-11-18
|
pubmed:meshHeading |
pubmed-meshheading:3894171-Adult,
pubmed-meshheading:3894171-Aged,
pubmed-meshheading:3894171-Clinical Trials as Topic,
pubmed-meshheading:3894171-Colitis, Ulcerative,
pubmed-meshheading:3894171-Double-Blind Method,
pubmed-meshheading:3894171-Enema,
pubmed-meshheading:3894171-Female,
pubmed-meshheading:3894171-Humans,
pubmed-meshheading:3894171-Intestinal Absorption,
pubmed-meshheading:3894171-Male,
pubmed-meshheading:3894171-Middle Aged,
pubmed-meshheading:3894171-Prednisolone
|
pubmed:year |
1985
|
pubmed:articleTitle |
Therapeutic benefits from a poorly absorbed prednisolone enema in distal colitis.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Controlled Clinical Trial
|