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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1985-8-19
|
| pubmed:abstractText |
In an attempt to investigate an aspect of the immunoregulatory mechanisms operating in alcoholic hepatic cirrhosis with ascites we have enumerated T-cell subsets in the peripheral blood and ascitic fluid of 16 patients with this disease. The peripheral blood analysis revealed a reduction of OKT3+, OKT4+ and OKT8+ cells compared to those of the control group (p less than 0.001) and an increase of OKT4+/OKT8+ ratio. In the ascitic fluid the OKT4+/OKT8+ ratio, compared to that of the peripheral blood, was decreased (p less than 0.001) because of increase of OKT8+ cell proportion. We suggest that the sequestrated splanchnic OKT8+ subset might be represented by suppressor lymphocytes transuding from the liver.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0021-2547
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
64
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
52-4
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:3890899-Adult,
pubmed-meshheading:3890899-Aged,
pubmed-meshheading:3890899-Antibodies, Monoclonal,
pubmed-meshheading:3890899-Ascitic Fluid,
pubmed-meshheading:3890899-Female,
pubmed-meshheading:3890899-Fluorescent Antibody Technique,
pubmed-meshheading:3890899-Humans,
pubmed-meshheading:3890899-Liver Cirrhosis, Alcoholic,
pubmed-meshheading:3890899-Male,
pubmed-meshheading:3890899-Middle Aged,
pubmed-meshheading:3890899-T-Lymphocytes
|
| pubmed:year |
1985
|
| pubmed:articleTitle |
Identification with monoclonal antibodies of T-cell subsets in peripheral blood and ascitic fluid of patients with alcoholic hepatic cirrhosis.
|
| pubmed:publicationType |
Journal Article
|