|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
1985-7-9
|
|
pubmed:abstractText |
CBA/Lac mice were immunosuppressed by thymectomy and whole body irradiation with 250 kVp X-rays following pretreatment with cytosine arabinoside. The optimum radiation dose for immunosuppression with prolonged survival was 7.35 Gy. The animals were kept in a standard animal unit with an overall survival rate of 83%. They were found to be suitable for large scale, long-term, xenotransplantation experiments at 20% of the cost of nude mice.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0023-6772
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
119-22
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:3889494-Animals,
pubmed-meshheading:3889494-Female,
pubmed-meshheading:3889494-Humans,
pubmed-meshheading:3889494-Immunosuppression,
pubmed-meshheading:3889494-Male,
pubmed-meshheading:3889494-Mice,
pubmed-meshheading:3889494-Mice, Inbred CBA,
pubmed-meshheading:3889494-Neoplasm Transplantation,
pubmed-meshheading:3889494-Radiation Dosage,
pubmed-meshheading:3889494-Thymectomy,
pubmed-meshheading:3889494-Transplantation, Heterologous,
pubmed-meshheading:3889494-Urinary Bladder Neoplasms,
pubmed-meshheading:3889494-Whole-Body Irradiation
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|
pubmed:year |
1985
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|
pubmed:articleTitle |
The suitability of immunosuppressed mice kept in a standard animal unit as recipients of human tumour xenografts.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
