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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1985-7-24
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pubmed:abstractText |
A randomized double-blind multicentre clinical trial was carried out to verify the effectiveness and tolerance of S-adenosylmethionine (SAMe) versus ibuprofen in 150 patients with hip and/or knee osteoarthritis. Both drugs were given orally 400 mg thrice daily for 30 days. SAMe exhibited a slightly more marked activity than the reference drug in the management of the various painful manifestations of the joint disease. Minor side-effects developed in five patients of SAMe group, and in 16 patients of ibuprofen group. No drop-outs occurred. No changes were observed in the routine laboratory tests.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0251-1649
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
5
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
N
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pubmed:pagination |
39-49
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:3888864-Aged,
pubmed-meshheading:3888864-Clinical Trials as Topic,
pubmed-meshheading:3888864-Double-Blind Method,
pubmed-meshheading:3888864-Female,
pubmed-meshheading:3888864-Hip Joint,
pubmed-meshheading:3888864-Humans,
pubmed-meshheading:3888864-Ibuprofen,
pubmed-meshheading:3888864-Knee Joint,
pubmed-meshheading:3888864-Male,
pubmed-meshheading:3888864-Middle Aged,
pubmed-meshheading:3888864-Osteoarthritis,
pubmed-meshheading:3888864-S-Adenosylmethionine
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pubmed:year |
1985
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pubmed:articleTitle |
Double-blind multicentre study of the activity of S-adenosylmethionine in hip and knee osteoarthritis.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|