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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1985-4-19
|
| pubmed:abstractText |
Calcium and magnesium metabolism was investigated in 10 hypertensive subjects with primary aldosteronism (seven adenomatous, three idiopathic). Serum levels of total calcium (9.03 +/- 0.2 mg/dl) and ionized calcium (2.06 +/- 0.06 meq/liter) were in the low-normal range, except for two patients who had levels of serum ionized calcium clearly above normal. Furthermore, both serum total (n = 6, p less than 0.01) and ionized calcium levels (n = 3) rose postoperatively in the patients who had an aldosterone-producing tumor removed. Dramatic elevations of parathyroid hormone levels (mean, 645 +/- 109 pgeq/liter; normal, less than 150 to 375 pgeq/liter) were seen in the majority of patients, including those two with frank ionized calcium elevations. Magnesium levels were within normal limits (2.07 +/- 0.07 meq/liter). These results indicate that parathyroid hypersecretion is a common feature of primary aldosteronism and also suggest a physiologic relationship between the activity of the renin-aldosterone system and parathyroid physiology. Sodium-volume expansion and negative calcium balance induced by aldosterone excess may predispose to hyperparathyroidism.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Aldosterone,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Magnesium,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium,
http://linkedlifedata.com/resource/pubmed/chemical/Renin
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0002-9343
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
78
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
385-90
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:3883768-Adenoma,
pubmed-meshheading:3883768-Adrenal Cortex Neoplasms,
pubmed-meshheading:3883768-Adrenalectomy,
pubmed-meshheading:3883768-Adult,
pubmed-meshheading:3883768-Aged,
pubmed-meshheading:3883768-Aldosterone,
pubmed-meshheading:3883768-Blood Pressure,
pubmed-meshheading:3883768-Calcium,
pubmed-meshheading:3883768-Female,
pubmed-meshheading:3883768-Humans,
pubmed-meshheading:3883768-Hyperaldosteronism,
pubmed-meshheading:3883768-Hypertension,
pubmed-meshheading:3883768-Magnesium,
pubmed-meshheading:3883768-Male,
pubmed-meshheading:3883768-Middle Aged,
pubmed-meshheading:3883768-Potassium,
pubmed-meshheading:3883768-Renin,
pubmed-meshheading:3883768-Renin-Angiotensin System,
pubmed-meshheading:3883768-Thyroid Gland,
pubmed-meshheading:3883768-Tomography, X-Ray Computed
|
| pubmed:year |
1985
|
| pubmed:articleTitle |
Calcium metabolism and parathyroid function in primary aldosteronism.
|
| pubmed:publicationType |
Journal Article
|