Linked Life Data

3879365

Source:http://linkedlifedata.com/resource/pubmed/id/3879365

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4-5
pubmed:dateCreated
1986-4-9
pubmed:abstractText
In an epidemiological study on the respiratory pathology of 1 100 iron miners, the alpha 1 protease inhibitor concentration (alpha 1 Pi) and the elastase inhibitory capacity (EIC) of serum were determined in 97 men with deficient Pi phenotype (73 MS, 24 MZ or S) compared with PiM non deficient men adjusted for age and tobacco consumption. There were differences in alpha 1 Pi concentration and in alpha 1 inhibitory capacity between phenotype groups in agreement with the results of other studies. Smoking produces an increase of serum alpha 1 Pi concentration and EIC in all Pi phenotype groups. This increase is more important (30%) in the MS group than in the others (MZ 20%, M 12%). This effect which appears to be related to smoking intensity does not seem to have a link with an alteration or a modification of the molecular function which is at a rate of 70% in all cases.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0398-7620
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
341-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Effect of smoking on the concentration and activity of serum alpha-1 anti-protease according to Pi phenotype].
pubmed:publicationType
Journal Article, English Abstract