|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1985-11-7
|
|
pubmed:abstractText |
Properdin factor B (Bf) phenotyping was carried out in 392 patients with rheumatoid arthritis (RA) and in 360 controls. In RA there were increased frequencies of both the Bf*S gene (83 vs 78%; pc = 0.0003) and the BfSS genotype 73 vs 61%; pc = 0.0002) and reduced frequencies of the Bf*F1 gene (0.5 vs 2.2%; pc = 0.03) and the BfFS genotype (20 vs 29%; pc = 0.0007). The frequencies of Bf*S in DR4 positive and DR4 negative RA were similar so that the findings were not accounted for by linkage disequilibrium between DR4 and Bf*S.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0315-162X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
12
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
456-7
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:3876434-Arthritis, Rheumatoid,
pubmed-meshheading:3876434-Complement Factor B,
pubmed-meshheading:3876434-Enzyme Precursors,
pubmed-meshheading:3876434-Gene Frequency,
pubmed-meshheading:3876434-Genetic Linkage,
pubmed-meshheading:3876434-Genetic Markers,
pubmed-meshheading:3876434-Genetic Variation,
pubmed-meshheading:3876434-Genotype,
pubmed-meshheading:3876434-HLA-DR4 Antigen,
pubmed-meshheading:3876434-Histocompatibility Antigens Class II,
pubmed-meshheading:3876434-Humans
|
|
pubmed:year |
1985
|
|
pubmed:articleTitle |
Genetic variants of properdin factor B (Bf) in rheumatoid arthritis.
|
|
pubmed:publicationType |
Journal Article
|
