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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
13
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pubmed:dateCreated |
1985-8-14
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pubmed:abstractText |
The ion transport properties of the rough endoplasmic reticulum (RER) from liver have been defined by using measurements of active and potential gradient-driven transport. The Ca2+ pump is shown to be electrogenic, and both ATP and potential difference is able to drive vanadate-inhibitable Ca2+ uptake into the RER. ATP-dependent Ca2+ transport into the RER depends on the presence of tetraethylammonium-sensitive cation conductance and a furosemide-inhibited cation/chloride cotransport pathway. Inositol trisphosphate does not affect either of the monovalent ion translocation systems but activates a Ca2+ conductance in the RER, allowing efflux of RER Ca2+ stores into the cytosol in exchange for K+ uptake.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-14907713,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-4585227,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6130541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6147898,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6188405,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6195158,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6197969,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6208363,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6288923,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6330778,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6334162,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6605482,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-6607924,
http://linkedlifedata.com/resource/pubmed/commentcorrection/3874400-672657
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Cesium,
http://linkedlifedata.com/resource/pubmed/chemical/Chlorides,
http://linkedlifedata.com/resource/pubmed/chemical/Furosemide,
http://linkedlifedata.com/resource/pubmed/chemical/Inositol 1,4,5-Trisphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/Inositol Phosphates,
http://linkedlifedata.com/resource/pubmed/chemical/Potassium,
http://linkedlifedata.com/resource/pubmed/chemical/Rubidium,
http://linkedlifedata.com/resource/pubmed/chemical/Sugar Phosphates,
http://linkedlifedata.com/resource/pubmed/chemical/Tetraethylammonium,
http://linkedlifedata.com/resource/pubmed/chemical/Tetraethylammonium Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/cesium chloride
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
82
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4433-7
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:3874400-Adenosine Triphosphate,
pubmed-meshheading:3874400-Animals,
pubmed-meshheading:3874400-Calcium,
pubmed-meshheading:3874400-Cesium,
pubmed-meshheading:3874400-Chlorides,
pubmed-meshheading:3874400-Electric Conductivity,
pubmed-meshheading:3874400-Endoplasmic Reticulum,
pubmed-meshheading:3874400-Furosemide,
pubmed-meshheading:3874400-Inositol 1,4,5-Trisphosphate,
pubmed-meshheading:3874400-Inositol Phosphates,
pubmed-meshheading:3874400-Liver,
pubmed-meshheading:3874400-Membrane Potentials,
pubmed-meshheading:3874400-Potassium,
pubmed-meshheading:3874400-Rats,
pubmed-meshheading:3874400-Rubidium,
pubmed-meshheading:3874400-Sugar Phosphates,
pubmed-meshheading:3874400-Tetraethylammonium,
pubmed-meshheading:3874400-Tetraethylammonium Compounds
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pubmed:year |
1985
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pubmed:articleTitle |
Inositol trisphosphate modification of ion transport in rough endoplasmic reticulum.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.
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