Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1985-8-12
|
pubmed:abstractText |
The incidence of serum organ and non-organ specific autoantibodies, the peripheral blood lymphocyte blastogenic response to phytohaemagglutinin, concanavalin A and pokeweek mitogen, and the surface markers of peripheral T and B lymphocytes were studied in 15 patients affected by coronary artery disease and in 21 patients with dilated cardiomyopathy. In the latter group there was a significantly impaired blastogenic response to concanavalin A with respect to both the normal control group and patients with coronary artery disease (P less than 0.01). The percentage of peripheral blood lymphocytes with cytotoxic/suppressor activity was also reduced in patients with dilated cardiomyopathy in comparison to normal subjects and patients with coronary artery disease (P less than 0.01 and P less than 0.05, respectively). These data may reflect an in vivo defect in suppressor cell function in patients with dilated cardiomyopathy.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0167-5273
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
8
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
113-23
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:3874172-Adolescent,
pubmed-meshheading:3874172-Adult,
pubmed-meshheading:3874172-Antibodies, Monoclonal,
pubmed-meshheading:3874172-Antibody Formation,
pubmed-meshheading:3874172-Autoantibodies,
pubmed-meshheading:3874172-B-Lymphocytes,
pubmed-meshheading:3874172-Cardiomyopathy, Dilated,
pubmed-meshheading:3874172-Coronary Disease,
pubmed-meshheading:3874172-Female,
pubmed-meshheading:3874172-Heart Failure,
pubmed-meshheading:3874172-Humans,
pubmed-meshheading:3874172-Leukocyte Count,
pubmed-meshheading:3874172-Lymphocyte Activation,
pubmed-meshheading:3874172-Lymphocytes,
pubmed-meshheading:3874172-Male,
pubmed-meshheading:3874172-Middle Aged,
pubmed-meshheading:3874172-Myocardium,
pubmed-meshheading:3874172-T-Lymphocytes
|
pubmed:year |
1985
|
pubmed:articleTitle |
Humoral immunity and lymphocyte subpopulations in patients with dilated cardiomyopathy.
|
pubmed:publicationType |
Journal Article
|