| pubmed-article:3873490 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3873490 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:3873490 | lifeskim:mentions | umls-concept:C0024141 | lld:lifeskim |
| pubmed-article:3873490 | lifeskim:mentions | umls-concept:C0150866 | lld:lifeskim |
| pubmed-article:3873490 | lifeskim:mentions | umls-concept:C0021027 | lld:lifeskim |
| pubmed-article:3873490 | lifeskim:mentions | umls-concept:C0021013 | lld:lifeskim |
| pubmed-article:3873490 | lifeskim:mentions | umls-concept:C1511790 | lld:lifeskim |
| pubmed-article:3873490 | lifeskim:mentions | umls-concept:C0282056 | lld:lifeskim |
| pubmed-article:3873490 | lifeskim:mentions | umls-concept:C0205332 | lld:lifeskim |
| pubmed-article:3873490 | lifeskim:mentions | umls-concept:C2828360 | lld:lifeskim |
| pubmed-article:3873490 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:3873490 | pubmed:dateCreated | 1985-7-24 | lld:pubmed |
| pubmed-article:3873490 | pubmed:abstractText | Cross-reactive anti-DNA antibody idiotypes have been identified on tissue-bound immunoglobulins from skin biopsies of patients with systemic lupus erythematosus (SLE) and discoid lupus erythematosus (DLE). Four polyclonal and two monoclonal anti-idiotypic reagents were used to screen biopsies from 24 patients with SLE, 23 patients with DLE, and 15 other patients with IgM-positive skin biopsies. Up to 46% of the SLE patients and 30% of the DLE patients were found to share idiotypes present on immunoglobulins deposited at the dermal-epidermal junction. Inhibition studies in four patients indicated that the idiotypes were on anti-DNA antibodies. In contrast, none of the anti-idiotypic antibodies bound to any of the control biopsies. These findings imply that some tissue-bound autoantibodies are derived from related families of high-frequency germ-line genes that are expressed in both SLE and DLE. | lld:pubmed |
| pubmed-article:3873490 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3873490 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3873490 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:3873490 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:3873490 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3873490 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3873490 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:3873490 | pubmed:issn | 0022-1767 | lld:pubmed |
| pubmed-article:3873490 | pubmed:author | pubmed-author:RauchJJ | lld:pubmed |
| pubmed-article:3873490 | pubmed:author | pubmed-author:BhogalB SBS | lld:pubmed |
| pubmed-article:3873490 | pubmed:author | pubmed-author:SchattnerAA | lld:pubmed |
| pubmed-article:3873490 | pubmed:author | pubmed-author:NaparstekYY | lld:pubmed |
| pubmed-article:3873490 | pubmed:author | pubmed-author:IsenbergDD | lld:pubmed |
| pubmed-article:3873490 | pubmed:author | pubmed-author:DudeneyCC | lld:pubmed |
| pubmed-article:3873490 | pubmed:author | pubmed-author:DugganDD | lld:pubmed |
| pubmed-article:3873490 | pubmed:author | pubmed-author:WojnaruskaFF | lld:pubmed |
| pubmed-article:3873490 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3873490 | pubmed:volume | 135 | lld:pubmed |
| pubmed-article:3873490 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3873490 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3873490 | pubmed:pagination | 261-4 | lld:pubmed |
| pubmed-article:3873490 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
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| pubmed-article:3873490 | pubmed:meshHeading | pubmed-meshheading:3873490-... | lld:pubmed |
| pubmed-article:3873490 | pubmed:meshHeading | pubmed-meshheading:3873490-... | lld:pubmed |
| pubmed-article:3873490 | pubmed:year | 1985 | lld:pubmed |
| pubmed-article:3873490 | pubmed:articleTitle | Detection of cross reactive anti-DNA antibody idiotypes on tissue-bound immunoglobulins from skin biopsies of lupus patients. | lld:pubmed |
| pubmed-article:3873490 | pubmed:publicationType | Journal Article | lld:pubmed |
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