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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1985-4-30
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pubmed:abstractText |
The prevalence of HLA-B27 in 88 patients with juvenile chronic arthritis was 22/88 (25%) with little variation among the 3 commonly recognized onset types. This was significantly more frequent than the prevalence of 9.4% in a Danish reference population. A strong association was found between the HLA-B27 antigen and 3 subgroups of patients: (1) boys with pauciarticular and late onset disease; (2) girls with apophyseal joint fusion; (3) a group of patients in whom the clinical picture was compatible with reactive arthritis or incomplete Reiter's syndrome. When these 3 subgroups were excluded from the total patient population, only 8 of the remaining 63 patients carried the B27 antigen, i.e., 13%, which was not significantly different from the prevalence in the reference population. Thus, the 3 subgroups account completely for the increase of B27 in the entire group of patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0315-162X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
119-22
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3872365-Adolescent,
pubmed-meshheading:3872365-Adult,
pubmed-meshheading:3872365-Arthritis,
pubmed-meshheading:3872365-Child,
pubmed-meshheading:3872365-Child, Preschool,
pubmed-meshheading:3872365-HLA Antigens,
pubmed-meshheading:3872365-HLA-B Antigens,
pubmed-meshheading:3872365-HLA-B27 Antigen,
pubmed-meshheading:3872365-Humans,
pubmed-meshheading:3872365-Male,
pubmed-meshheading:3872365-Sex Factors,
pubmed-meshheading:3872365-Time Factors
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pubmed:year |
1985
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pubmed:articleTitle |
HLA-B27 in juvenile chronic arthritis.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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