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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1979-12-29
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pubmed:abstractText |
A 2.5 kg thoracopagus (Siamese) twin and a 0.73 kg premature newborn developed systemic candidiasis and were treated with intravenous miconazole. The conjoined twin was in a state of severe metabolic acidosis, respiratory distress, jaundice, anuria, abdominal distension, and shock. The 0.73 kg premature infant was also in a state of severe metabolic acidosis, respiratory distress, and oliguria. Miconazole was used in this desperate situation for the treatment of life-threatening candidiasis. Both infants responded well to treatment and recovered. All parameters of their diseases improved during therapy despite pre-existing multiple organ dysfunction. Miconazole can be a safe alternative to amphotericin B for the treatment of systemic candidiasis in neonatal infants, including those with impaired renal function.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0002-9610
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
138
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
688-91
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:386810-Candida albicans,
pubmed-meshheading:386810-Candidiasis,
pubmed-meshheading:386810-Humans,
pubmed-meshheading:386810-Imidazoles,
pubmed-meshheading:386810-Infant,
pubmed-meshheading:386810-Infant, Newborn,
pubmed-meshheading:386810-Infant, Premature, Diseases,
pubmed-meshheading:386810-Male,
pubmed-meshheading:386810-Miconazole,
pubmed-meshheading:386810-Sepsis,
pubmed-meshheading:386810-Twins, Conjoined
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pubmed:year |
1979
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pubmed:articleTitle |
Miconazole therapy for systemic candidiasis in a conjoined (Siamese) twin and a premature newborn.
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pubmed:publicationType |
Journal Article,
Case Reports
|