Switch to
Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
20
|
pubmed:dateCreated |
1979-12-20
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pubmed:abstractText |
In a randomized double-blind multicenter trial, 15 outpatients with endoscopically proved anastomotic ulceration after Billroth I or Billroth II partial gastrectomy received cimetidine, 1 g daily over eight weeks, or a placebo. All patients also received antiacid. The ulcer healed completely in all seven cimetidine-treated patients and in one of the eight placebo-treated patients (P less than 0.01). Ulcers not healed during the double-blind phase of the trial were all subsequently healed on open cimetidine treatment. There was a trend toward improvement of daytime symptoms in favor of cimetidine (P = 0.06), and nighttime symptoms were significantly relieved during the initial four weeks of cimetidine treatment P = 0.02). We conclude that cimetidine, 1 g daily, promotes healing of anastomotic ulcers after partial gastrectomy.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0028-4793
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
301
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1077-80
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:386125-Adult,
pubmed-meshheading:386125-Antacids,
pubmed-meshheading:386125-Cimetidine,
pubmed-meshheading:386125-Clinical Trials as Topic,
pubmed-meshheading:386125-Female,
pubmed-meshheading:386125-Gastrectomy,
pubmed-meshheading:386125-Guanidines,
pubmed-meshheading:386125-Humans,
pubmed-meshheading:386125-Male,
pubmed-meshheading:386125-Middle Aged,
pubmed-meshheading:386125-Postoperative Complications,
pubmed-meshheading:386125-Random Allocation,
pubmed-meshheading:386125-Stomach Ulcer
|
pubmed:year |
1979
|
pubmed:articleTitle |
Cimetidine for anastomotic ulcers after partial gastrectomy. A randomized controlled trial.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
|