| pubmed-article:3858829 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3858829 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3858829 | lifeskim:mentions | umls-concept:C0330390 | lld:lifeskim |
| pubmed-article:3858829 | lifeskim:mentions | umls-concept:C1333247 | lld:lifeskim |
| pubmed-article:3858829 | lifeskim:mentions | umls-concept:C0024518 | lld:lifeskim |
| pubmed-article:3858829 | lifeskim:mentions | umls-concept:C0162326 | lld:lifeskim |
| pubmed-article:3858829 | lifeskim:mentions | umls-concept:C1524075 | lld:lifeskim |
| pubmed-article:3858829 | lifeskim:mentions | umls-concept:C0018591 | lld:lifeskim |
| pubmed-article:3858829 | lifeskim:mentions | umls-concept:C0456387 | lld:lifeskim |
| pubmed-article:3858829 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:3858829 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:3858829 | pubmed:dateCreated | 1985-6-25 | lld:pubmed |
| pubmed-article:3858829 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3858829 | pubmed:abstractText | Two HLA class II beta-chain clones from a cell line homozygous for the DR1 haplotype have been characterized and sequenced. They represent a DR beta chain (2918.4) and a DQ beta chain (2918.8). Clone 2918.4 has been used to select mRNA from a lymphoblastoid cell line, and this was injected into Xenopus oocytes with mRNA selected with a DR alpha chain. The translation products were immunoprecipitated with a beta-chain-specific monoclonal antibody and electrophoresed on two-dimensional gels. This revealed positive signals in the positions predicted for beta and alpha chains. Sequence comparisons of 2918.4 with previously published DR beta-chain sequences confirm the presence of two regions of variability in the membrane distal domain. Analysis of the sequence of 2918.8 identified it as a DQ beta chain identical to one previously published from a DR3,w6 cell line. We speculate, therefore, that the DQ beta sequence represents the DQ1 specificity shared by the DR1 and DRw6 haplotypes. | lld:pubmed |
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| pubmed-article:3858829 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3858829 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3858829 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3858829 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3858829 | pubmed:month | May | lld:pubmed |
| pubmed-article:3858829 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:3858829 | pubmed:author | pubmed-author:McDevittH OHO | lld:pubmed |
| pubmed-article:3858829 | pubmed:author | pubmed-author:CONER ARA | lld:pubmed |
| pubmed-article:3858829 | pubmed:author | pubmed-author:EstessPP | lld:pubmed |
| pubmed-article:3858829 | pubmed:author | pubmed-author:St JohnTT | lld:pubmed |
| pubmed-article:3858829 | pubmed:author | pubmed-author:SaijoKK | lld:pubmed |
| pubmed-article:3858829 | pubmed:author | pubmed-author:ErlichH AHA | lld:pubmed |
| pubmed-article:3858829 | pubmed:author | pubmed-author:WatlingD LDL | lld:pubmed |
| pubmed-article:3858829 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3858829 | pubmed:volume | 82 | lld:pubmed |
| pubmed-article:3858829 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3858829 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3858829 | pubmed:pagination | 3405-9 | lld:pubmed |
| pubmed-article:3858829 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:3858829 | pubmed:year | 1985 | lld:pubmed |
| pubmed-article:3858829 | pubmed:articleTitle | DNA sequence and characterization of human class II major histocompatibility complex beta chains from the DR1 haplotype. | lld:pubmed |
| pubmed-article:3858829 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3858829 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3858829 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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