Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
1985-6-25
pubmed:abstractText
The mitochondrial respiratory system is differentially produced during the life cycle of the parasitic protozoan, Trypanosoma brucei. We have found 14 transcripts that are derived from a maxicircle (mitochondrial DNA) region that contains sequences homologous to cytochrome c oxidase subunits I and II, unassigned reading frame 1 from mitochondrial DNA of other organisms, and two other open reading frames. Ten of these transcripts occur as pairs that differ in size by approximately equal to 200 nucleotides. While most of these transcripts occur in both life cycle forms, four transcripts are differentially expressed. Of these, two are more abundant in bloodstream forms, one is more abundant in procyclic forms, and one is present in procyclic but not bloodstream forms. These results indicate that the differential production of the mitochondrial respiratory system in T. brucei entails regulation of mitochondrial transcriptional and/or posttranscriptional processes.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-388356, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-4762559, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6088073, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6093040, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6095184, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6159641, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6162570, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6185497, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6267635, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6306559, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6310323, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6314266, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6327737, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6330736, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6366549, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6439844, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6513991, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6547230, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6771018, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6771020, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6825172, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-6927793, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-7039847, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-7051964, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-881736, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-911786, http://linkedlifedata.com/resource/pubmed/commentcorrection/3858825-978727
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3380-4
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Differential expression of mitochondrial genes between life cycle stages of Trypanosoma brucei.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.