Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
165
pubmed:dateCreated
1985-7-24
pubmed:abstractText
A high number of structurally altered marker chromosomes was found in two cases of ovarian carcinoma. Even by the application of different staining methods it was not possible to identify all the chromosomes. No evidence for the existence of a translocation between chromosomes 6 and 14 was found, which seems to be a specific abnormality characteristic of papillary serous cystadenocarcinomas of the ovary. It is of interest that double minutes were present in both cases. This offers further evidence for the assumption that double minutes are not infrequent in carcinomas. Their orthodox mitotic behaviour leads to high karyotype variability (number of double minutes/cell), and may be of particular importance for tumour biology. The methodological and cytogenetic implications of the results are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0011-4529
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
15-24
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Cytogenetic observations on two ovarian carcinomas with double minutes, one with a 6q- marker chromosome.
pubmed:publicationType
Journal Article