Linked Life Data

3841264

Source:http://linkedlifedata.com/resource/pubmed/id/3841264

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1986-2-19
pubmed:abstractText
Activity of terminal deoxynucleotidyl transferase (TdT) was measured in the thymus of 8- to 14-week-old kittens. Microscopic evidence of involution or other morphologic changes were not observed in formalin-fixed hematoxylin and eosin-stained thymic tissue sections. Thymic tissue from young kittens (8 weeks old) had low TdT activity, as determined by enzymatic catalysis or immunoassay procedures. Markedly higher TdT activity was measured in thymic tissue of older kittens (13 to 14 weeks old). Feline TdT catalyzed the polymerization of deoxynucleotides at a higher rate in Mn2+ than in Mg2+. Results of protein immunoblotting experiments indicated that the major form of feline thymic TdT is a single, high molecular weight polypeptide in 13- to 14-week-old kittens. Detection of TdT activity in the feline thymus indicated that TdT may have the same diagnostic and therapeutic value in feline oncology as in human oncology.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0002-9645
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2616-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Terminal deoxynucleotidyl transferase activity in thymocytes of kittens.
pubmed:publicationType
Journal Article