Linked Life Data

3840711

Source:http://linkedlifedata.com/resource/pubmed/id/3840711

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
685
pubmed:dateCreated
1985-12-31
pubmed:abstractText
CHIP (cis-dichlorobis isopropylamine trans-dihydroxy platinum IV) is a second-generation platinum co-ordination complex which potentiates the effects of radiation. Comparisons of the biological effects of CHIP and X rays upon Chinese hamster (ovary) cells have shown similarities with respect to the shape of the dose-response curves, clone size distributions and perturbation of the cell cycle. Unlike irradiated cells however, CHIP-treated cells showed no recovery from sublethal damage and no variation in sensitivity throughout the cell cycle. CHIP is a radiomimetic drug in some respects but not in others.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0007-1285
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
51-62
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
The radiomimetic properties of a platinum drug.
pubmed:publicationType
Journal Article, Comparative Study, In Vitro, Research Support, Non-U.S. Gov't