Linked Life Data

3840207

Source:http://linkedlifedata.com/resource/pubmed/id/3840207

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1985-11-5
pubmed:abstractText
The cell membrane markers on peripheral blood lymphocytes of 10 patients with Vogt-Koyanagi-Harada disease (VKH) were analyzed by laser flow cytometry using monoclonal antibodies. Seven patients with active uveitis and 98 normal control subjects were also studied. The percentage of OKT3+, OKT4+ and OKT11+ cells were significantly lower while OKIa1+ cell were higher in VKH compared to controls. The percentage of cells reacting with monoclonal antibodies were slightly affected during steroid therapy, but returned to the pretreatment level after cessation of the therapy. OKIa1+ cells were shown to be increased in active uveitis while percentages of cells with other cell markers remained unchanged when the results were compared with that of the control. The findings suggest that the analysis of cell membrane markers on lymphocytes in VKH could be a significant parameter in clinical medicine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0141-2760
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
49-52
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Surface markers of peripheral blood lymphocytes in Vogt-Koyanagi-Harada disease.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't