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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4-5
|
pubmed:dateCreated |
1986-9-23
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pubmed:abstractText |
Nuclear magnetic resonance spectroscopy is increasingly used to study cellular metabolism in a manner respecting cell integrity. The contribution of phosphorus-31 and carbon-13 NMR is discussed and illustrated by specific examples taken from work carried out in this laboratory or from the literature. A particular emphasis is layed on metabolite identification, quantitation and fluxes as studied by phosphorus-31 NMR which provides a direct insight of energy metabolism. The analysis of perfused rat liver by natural abundance carbon-13 NMR illustrates the potential of the method of study non-invasively lipid and carbohydrate metabolism in living systems. The use of carbon-13 enriched substrates to pinpoint a specific pathway of the intermediary metabolism is described in the case of excised rat heart and liver perfused with (2-C13)-acetate. Clinical applications of NMR spectroscopy are rapidly reviewed.
|
pubmed:language |
fre
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0003-4266
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
46
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
239-47
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3837630-Adenine Nucleotides,
pubmed-meshheading:3837630-Adenocarcinoma,
pubmed-meshheading:3837630-Animals,
pubmed-meshheading:3837630-Carbon,
pubmed-meshheading:3837630-Cell Line,
pubmed-meshheading:3837630-Cells,
pubmed-meshheading:3837630-Colonic Neoplasms,
pubmed-meshheading:3837630-Humans,
pubmed-meshheading:3837630-Liver,
pubmed-meshheading:3837630-Magnetic Resonance Spectroscopy,
pubmed-meshheading:3837630-Myocardium,
pubmed-meshheading:3837630-Phosphocreatine,
pubmed-meshheading:3837630-Phosphorus,
pubmed-meshheading:3837630-Rats,
pubmed-meshheading:3837630-Spectrum Analysis
|
pubmed:year |
1985
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pubmed:articleTitle |
[Nuclear magnetic resonance spectroscopy. New tool for investigating cellular metabolism in living systems].
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
|