Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1986-7-28
pubmed:abstractText
Central sensory nerve fibers were examined at distal (C3) and proximal (D12) levels of the gracile tract in the spontaneously diabetic BB-rat. Ultrastructural findings included early occurring malorientation of axoplasmic neurofilaments, axonal sequestration by honeycombing, and ensuing progressive axonal atrophy followed by Wallerian degeneration. Quantification of qualitative findings revealed a proximal to distal gradient in severity. Morphometric analysis confirmed a progressive myelinated fiber atrophy, which was more severe at the distal level. These findings are similar to those earlier described in peripheral sensory nerves of this model. Taken in concert with these previous findings, we conclude that the distal mainly sensory polyneuropathy in the diabetic BB-rat can be classified as a central-peripheral distal axonopathy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0168-8227
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
289-98
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Central-peripheral distal axonopathy in the spontaneously diabetic BB-rat: ultrastructural and morphometric findings.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't