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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1987-5-6
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pubmed:abstractText |
The classical Whipple procedure for chronic pancreatitis has been associated with significant long term postoperative morbidity. The pylorus-preserving procedure of Longmire has reduced but not eliminated the long-term morbidity. Preservation of the whole duodenum with total pancreatectomy has been introduced for the treatment of patients with end-stage chronic pancreatitis after favourable experience with this procedure in infants for nesidioblastosis. Fourteen patients with chronic pancreatitis have had a total pancreatectomy with preservation of the duodenum and the bile duct. All patients are still alive (median follow-up 9.5 months) and none suffered major complications in the perioperative period. One patient developed a biliary stricture at 3 months, requiring biliary reconstruction. Six of the patients have returned to full-time work; nine require no analgesia. All patients require pancreatic enzyme replacement, and all patients have gained weight postoperatively. Diabetic control is satisfactory with a twice daily insulin regime. Duodenum-preserving total pancreatectomy is feasible in the adult without mortality or high morbidity; early experience suggests that preserving the duodenum improves gastrointestinal function with easier control of the diabetes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0007-1323
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
74
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
35-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3828733-Adult,
pubmed-meshheading:3828733-Chronic Disease,
pubmed-meshheading:3828733-Duodenum,
pubmed-meshheading:3828733-Female,
pubmed-meshheading:3828733-Follow-Up Studies,
pubmed-meshheading:3828733-Humans,
pubmed-meshheading:3828733-Male,
pubmed-meshheading:3828733-Middle Aged,
pubmed-meshheading:3828733-Pancreatectomy,
pubmed-meshheading:3828733-Pancreatitis,
pubmed-meshheading:3828733-Postoperative Period
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pubmed:year |
1987
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pubmed:articleTitle |
Duodenum-preserving total pancreatectomy for end stage chronic pancreatitis.
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pubmed:publicationType |
Journal Article
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