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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1987-3-30
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pubmed:abstractText |
The vitamin K-dependent proteins involved in blood coagulation processes each contain a small cystine loop with the sequence -Gla-Cys-X-Gla-Gla-X-Cys-. A method for the synthesis of the heptapeptide derivative representing the 17-23 sequence of bovine prothrombin, Z-Gla-Cys-Leu-Gla-Gla-Pro-Cys-OBzl, has been developed. The 25Mg2+ n.m.r. spectrum of the heptapeptide derivative has been obtained and is compared to the n.m.r. spectra obtained from the interaction of 25Mg2+ with Z-Gla-OMe and Z-Gla-Gla-OMe.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0367-8377
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
569-78
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:3818174-1-Carboxyglutamic Acid,
pubmed-meshheading:3818174-Amino Acid Sequence,
pubmed-meshheading:3818174-Animals,
pubmed-meshheading:3818174-Cattle,
pubmed-meshheading:3818174-Magnesium,
pubmed-meshheading:3818174-Magnetic Resonance Spectroscopy,
pubmed-meshheading:3818174-Oligopeptides,
pubmed-meshheading:3818174-Protein Binding,
pubmed-meshheading:3818174-Prothrombin
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pubmed:year |
1986
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pubmed:articleTitle |
Synthesis of a gamma-carboxyglutamic acid containing heptapeptide corresponding to bovine prothrombin residues 17-23.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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