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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1987-3-30
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pubmed:abstractText |
A rapid and simple technique for assessing ovulation and luteal function is needed in clinical practice. A sensitive immunoassay kit is presented here for clinical use. An immunoassay of pregnanediol-3-glucuronide (Pd-3G) in urine was established. The sensitivity of this assay was 0.4 mg/l of Pd-3G. The standard error range of the recovery test was within 0.8 mg/l, and the coefficients of variation of within-run and day-to-day precision test were within 4%. Cross reactions of various steroids were observed in free pregnanediol, pregnanetriol and progesterone, but their reactivity exhibited less than 4%. The Pd-3G/creatinine (mg/g) ratio was demonstrated as nearly constant over a 24-hour period. A significant rise of Pd-3G coincided with a luteinizing hormone surge and continued during the luteal phase in the ovulatory menstrual cycle. In an anovulatory cycle, Pd-3G was found to be under 4 mg/g creatinine. This Pd-3G direct-assay method could be widely used in infertility clinics.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0378-7346
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
186-93
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:3817603-Adult,
pubmed-meshheading:3817603-Anovulation,
pubmed-meshheading:3817603-Circadian Rhythm,
pubmed-meshheading:3817603-Female,
pubmed-meshheading:3817603-Humans,
pubmed-meshheading:3817603-Immunoassay,
pubmed-meshheading:3817603-Infertility, Female,
pubmed-meshheading:3817603-Luteal Phase,
pubmed-meshheading:3817603-Ovulation Detection,
pubmed-meshheading:3817603-Pregnanediol,
pubmed-meshheading:3817603-Quality Control
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pubmed:year |
1986
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pubmed:articleTitle |
Rapid immunochemical assay of pregnanediol-3-glucuronide in urine and its clinical application.
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pubmed:publicationType |
Journal Article
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