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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1987-4-16
|
| pubmed:abstractText |
The drugs in the FAM combination (fluorouracil, doxorubicin, mitomycin) were tested for a possible effect on monocyte function by means of a glass-surface fluorescence-quenching technique of monocyte phagocytosis. The individual drugs significantly inhibited monocyte phagocytosis. The inhibition was located at the engulfment phase of phagocytosis and in an order of magnitude of 20-30%. The FAM combination did not suppress monocyte phagocytosis more than each one of the individual drugs. It is suggested that a slight inhibition of monocyte phagocytosis is a cost of cytotoxic treatment.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0748-7983
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
51-5
|
| pubmed:dateRevised |
2007-7-2
|
| pubmed:meshHeading |
pubmed-meshheading:3817166-Cell Adhesion,
pubmed-meshheading:3817166-Doxorubicin,
pubmed-meshheading:3817166-Fluorouracil,
pubmed-meshheading:3817166-Humans,
pubmed-meshheading:3817166-Mitomycins,
pubmed-meshheading:3817166-Monocytes,
pubmed-meshheading:3817166-Phagocytosis,
pubmed-meshheading:3817166-Yeasts
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
Phagocytosis of yeast cells by monocytes: effects of fluorouracil, doxorubicin and mitomycin.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|