Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2 Pt 2
pubmed:dateCreated
1987-3-24
pubmed:abstractText
Postnatal phase setting of pup circadian rhythm by nursing mother was examined in rats by mother-pup exchange experiments. To know the effect of phase reversal of the nursing mother, pups were exchanged after birth so that a mother rat raised pups, half of which were born to her and the other half which came from a reversed mother, and activity onset and offset of pup locomotor rhythm were measured at weaning. Effects of litter size were also examined. Direct entrainment to light-dark cycles was excluded by blinding pups. In the unexchanged group, a strong positive correlation was detected between the phase of the circadian rhythm at weaning and the free-running period measured after weaning. The area covered by the 99% confidence interval of the regression line was used for the phase reference zone, and the circadian rhythm of an exchanged pup whose phase at weaning was located outside the reference zone was regarded as having been influenced by the nursing mother. The complete phase reversal occurred in two out of seven exchanged pups when litter size was relatively large (n = 5-7) and in 9 out of 11 when litter size was small (n = 2). It is concluded that the nursing mother rat is capable of phase setting the circadian locomotor rhythm of blinded pups. This maternal effect seems to be related to litter size.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0002-9513
pubmed:author
pubmed:issnType
Print
pubmed:volume
252
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
R256-61
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Phase setting of circadian locomotor rhythm of infant rats.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't