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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1987-2-26
|
| pubmed:abstractText |
Residual incorporation of 3H-thymidine into acid insoluble fraction was inhibited a few hours and stimulated 24 hours following gamma-irradiation (60Co) of a stationary culture of HeLa cells with doses of 5 to 50 Gy. The dose-response curve for the stimulated incorporation reached a maximum at a dose of about 10 Gy. Hydroxyurea (10 mM) was shown to suppress the incorporation. The authors suggest that ionizing radiation induces a transfer of resting cells to the S phase-like state.
|
| pubmed:language |
rus
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0033-8192
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
800-2
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:3809415-DNA,
pubmed-meshheading:3809415-DNA Damage,
pubmed-meshheading:3809415-DNA Replication,
pubmed-meshheading:3809415-Dose-Response Relationship, Radiation,
pubmed-meshheading:3809415-Gamma Rays,
pubmed-meshheading:3809415-HeLa Cells,
pubmed-meshheading:3809415-Humans,
pubmed-meshheading:3809415-Hydroxyurea,
pubmed-meshheading:3809415-Kinetics,
pubmed-meshheading:3809415-Thymidine,
pubmed-meshheading:3809415-Tritium
|
| pubmed:articleTitle |
[DNA synthesis in a stationary HeLa cell culture following gamma irradiation].
|
| pubmed:publicationType |
Journal Article,
English Abstract
|