Linked Life Data

3806402

Source:http://linkedlifedata.com/resource/pubmed/id/3806402

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1987-3-26
pubmed:abstractText
The glutathione content of freshly isolated rabbit alveolar type II cells, Clara cells and macrophages was depleted by incubating with diethyl maleate and the ability of these cell types to resynthesize glutathione from the sulfur-containing amino acids, cysteine, cystine and methionine was determined. Cysteine and methionine were taken up at a similar rate into each of the cell types, with cystine uptake occurring at a 10- to 14-fold lower rate. The cells were best able to utilize cysteine for glutathione resynthesis and the rates of both uptake and synthesis were fastest in macrophages and slowest in type II cells. There was no evidence for participation of a cystathionine pathway for glutathione synthesis in any of the cell types.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-3565
pubmed:author
pubmed:issnType
Print
pubmed:volume
240
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
376-80
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1987
pubmed:articleTitle
Glutathione biosynthesis from sulfur-containing amino acids in enriched populations of Clara and type II cells and macrophages freshly isolated from rabbit lung.
pubmed:publicationType
Journal Article, In Vitro