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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1987-3-23
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pubmed:abstractText |
Nine patients with hematologic malignancies developed fungal infections, predominantly involving the liver and spleen. Eight patients had biopsy-documented progressive candidiasis and one had an unclassified fungus. The patients were treated with liposomal-amphotericin B (L-AmpB) after their fungal infection progressed during treatment with standard intravenous (IV) AmpB (Fungizone; E. R. Squibb & Son, Princeton, NJ) and/or other antifungals. Eight patients (88.8%) were cured of their fungal infection, and one showed improvement after treatment. Minor acute toxicity and no chronic toxicity were associated with the administration of L-AmpB. L-AmpB is a safe and effective therapeutic method for treating fungal infections that have invaded the liver and spleen even when they are refractory to conventional anti-fungal therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0732-183X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
310-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3806172-Adolescent,
pubmed-meshheading:3806172-Adult,
pubmed-meshheading:3806172-Amphotericin B,
pubmed-meshheading:3806172-Candidiasis,
pubmed-meshheading:3806172-Child, Preschool,
pubmed-meshheading:3806172-Female,
pubmed-meshheading:3806172-Humans,
pubmed-meshheading:3806172-Leukemia,
pubmed-meshheading:3806172-Liposomes,
pubmed-meshheading:3806172-Liver Diseases,
pubmed-meshheading:3806172-Lymphoma,
pubmed-meshheading:3806172-Male,
pubmed-meshheading:3806172-Middle Aged,
pubmed-meshheading:3806172-Splenic Diseases
|
pubmed:year |
1987
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pubmed:articleTitle |
Treatment of hepatosplenic candidiasis with liposomal-amphotericin B.
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|