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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
|
pubmed:dateCreated |
1979-9-17
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pubmed:abstractText |
In an open study dl-phenylalanine in doses from 75--200 mg/day was administered to 20 depressed patients for 20 days. At the end of the trial 12 patients (8 with complete, 4 with good response) could be discharged without any further treatment. 4 patients with partially untypical depressions experienced mild to moderate responses, whereas 4 patients did not respond at all to the phenylalanine administration. Depressive "core symptoms" as depressed mood, retardation and/or agitation were preferentially, anxiety and sleep disturbances moderately and hypochondriasis and compulsiveness were not influenced. It is concluded that dl-phenylalanine might have substantial antidepressant properties and that further controlled investigations are justified.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0004-4172
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
28
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1283-4
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:380577-Adult,
pubmed-meshheading:380577-Aged,
pubmed-meshheading:380577-Clinical Trials as Topic,
pubmed-meshheading:380577-Depression,
pubmed-meshheading:380577-Female,
pubmed-meshheading:380577-Humans,
pubmed-meshheading:380577-Male,
pubmed-meshheading:380577-Middle Aged,
pubmed-meshheading:380577-Phenylalanine,
pubmed-meshheading:380577-Placebos,
pubmed-meshheading:380577-Time Factors
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pubmed:year |
1978
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pubmed:articleTitle |
[DL-phenylalanine as an antidepressant. Open study (author's transl)].
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pubmed:publicationType |
Journal Article,
Clinical Trial,
English Abstract
|