|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1987-3-3
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|
pubmed:abstractText |
Rats were intravenously administered (14C)-2-ethylhexyl acrylate at the dose 10 mg/kg or 50 mg/kg b. w. Biliary excretion of 14C-radioactivity was followed in 1-3 hour intervals within the first 24 hours after administration. The rats were then sacrificed and distribution of 14C-radioactivity was followed in some organs. Highest radioactivity was found in liver, less in the kidneys and the least in the brain. A significant increase of bile flow was observed. In the 24-hour intervals 2.2% of the dose was eliminated via bile at both dosages, most of it (83%) during the first 3 hours.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
0022-1732
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
30
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
365-70
|
|
pubmed:dateRevised |
2003-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:3805709-Acrylates,
pubmed-meshheading:3805709-Air Pollutants, Occupational,
pubmed-meshheading:3805709-Animals,
pubmed-meshheading:3805709-Bile,
pubmed-meshheading:3805709-Carbon Radioisotopes,
pubmed-meshheading:3805709-Glutathione,
pubmed-meshheading:3805709-Male,
pubmed-meshheading:3805709-Rats,
pubmed-meshheading:3805709-Rats, Inbred Strains,
pubmed-meshheading:3805709-Tissue Distribution
|
|
pubmed:year |
1986
|
|
pubmed:articleTitle |
Biliary excretion and organ distribution of 14C radioactivity after 14C-2-ethylhexyl acrylate administration in rats.
|
|
pubmed:publicationType |
Journal Article
|
