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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1987-3-6
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pubmed:abstractText |
Retinal S antigen is a potent autoantigen used for the induction of experimental allergic uveoretinitis (EAU). EAU is an organ-specific disease and shows many similarities to other autoimmune diseases such as experimental encephalomyelitis. This paper describes the preparation of highly purified S antigen by using a one-step ion-exchange method. High yields of the protein were obtained. S antigen prepared by this method induces a prolonged posterior uveoretinitis with cellular infiltration in the vitreous and specific loss of retinal photoreceptor cells. The purity of the protein was checked by silver-stained SDS-polyacrylamide gels and immunoblotting techniques.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
|
pubmed:issn |
0165-5728
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
99-108
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:3805262-Animals,
pubmed-meshheading:3805262-Antigens,
pubmed-meshheading:3805262-Arrestin,
pubmed-meshheading:3805262-Cattle,
pubmed-meshheading:3805262-Chromatography, Ion Exchange,
pubmed-meshheading:3805262-Chromatography, Liquid,
pubmed-meshheading:3805262-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:3805262-Eye Proteins,
pubmed-meshheading:3805262-Immune Sera,
pubmed-meshheading:3805262-Rabbits
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pubmed:year |
1987
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pubmed:articleTitle |
A simplified method for the isolation of highly purified bovine retinal S antigen.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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