Linked Life Data

3801569

Source:http://linkedlifedata.com/resource/pubmed/id/3801569

Statements in which the resource exists.
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pubmed-article:3801569pubmed:abstractTextA series of N-acyl sphingomyelins (C16:0, C18:0, C20:0, C22:0, and C24:0) have been synthesized and single bilayer vesicles formed by sonication and ultracentrifugation. X-ray scattering data have been collected from the sphingomyelin vesicles at 50 degrees C in the melted-chain state. The x-ray scattering data have been transformed to the corresponding Patterson functions and Fourier electron density profiles; analysis of these functions has provided the intrabilayer phosphate-phosphate separation dp-p, a measure of the lipid bilayer thickness. The bilayer thickness increases linearly with increasing chain length (increment 1.3-1.4 A) and the intercept, 14.3-15.0 A, suggests a contribution of 7.0-7.5 A for each phosphorylcholine group to the bilayer thickness. The electron-density profiles have features suggestive of chain interdigitation when the length of the N-acyl chain (C20:0, C22:0, and C24:0) exceeds significantly the length of the invariant sphingosine chain.lld:pubmed
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pubmed-article:3801569pubmed:authorpubmed-author:ShipleyG GGGlld:pubmed
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pubmed-article:3801569pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:3801569pubmed:year1986lld:pubmed
pubmed-article:3801569pubmed:articleTitleX-ray scattering of vesicles of N-acyl sphingomyelins. Determination of bilayer thickness.lld:pubmed
pubmed-article:3801569pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:3801569pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
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