Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1987-3-20
pubmed:abstractText
A series of N-acyl sphingomyelins (C16:0, C18:0, C20:0, C22:0, and C24:0) have been synthesized and single bilayer vesicles formed by sonication and ultracentrifugation. X-ray scattering data have been collected from the sphingomyelin vesicles at 50 degrees C in the melted-chain state. The x-ray scattering data have been transformed to the corresponding Patterson functions and Fourier electron density profiles; analysis of these functions has provided the intrabilayer phosphate-phosphate separation dp-p, a measure of the lipid bilayer thickness. The bilayer thickness increases linearly with increasing chain length (increment 1.3-1.4 A) and the intercept, 14.3-15.0 A, suggests a contribution of 7.0-7.5 A for each phosphorylcholine group to the bilayer thickness. The electron-density profiles have features suggestive of chain interdigitation when the length of the N-acyl chain (C20:0, C22:0, and C24:0) exceeds significantly the length of the invariant sphingosine chain.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-13641241, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-217404, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-3730380, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-4371833, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-4859496, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-5279041, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-5693705, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-573625, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-6518252, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-6631959, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-6854643, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-6854644, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-687759, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-7220788, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-7306486, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-889789, http://linkedlifedata.com/resource/pubmed/commentcorrection/3801569-901797
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0006-3495
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1071-7
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
X-ray scattering of vesicles of N-acyl sphingomyelins. Determination of bilayer thickness.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.