Linked Life Data

3794787

Source:http://linkedlifedata.com/resource/pubmed/id/3794787

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1987-2-10
pubmed:abstractText
In the previous paper, we experimentally analyzed the selective affinity of the pCC growth cone for the MP1/dMP2 fascicle in the grasshopper embryo. Here we describe a similar experimental analysis demonstrating the selective affinity of the aCC growth cone for the U fascicle. These results support the labeled-pathways hypothesis. The 2 sets of cell ablation experiments argue against the simple location of axons, the simple timing of axon outgrowth, and/or simple quantitative differences in the expression of a common surface label being the major determinant in pathway selection by neuronal growth cones. Rather, these 2 examples of growth-cone specificity, together with previous studies on the G growth cone, suggest that neuronal recognition molecules are differentially expressed on the surfaces of different embryonic axonal pathways and tracts and are used to guide growth cones through a series of choice points to their targets.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0270-6474
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
3532-41
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Guidance of neuronal growth cones in the grasshopper embryo. II. Recognition of a specific axonal pathway by the aCC neuron.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't