Linked Life Data

3792486

Source:http://linkedlifedata.com/resource/pubmed/id/3792486

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1987-2-5
pubmed:abstractText
72 male and 72 female rats of the strain Can-Hoe-Wiga received standard diet in a long-term study (24 months). A group of equal size received the beta-blocker BM 51.052 administered at a dose of 900 ppm in the feed. The animals in the drug group showed a 20 to 30% delay in body weight gain in comparison with the control animals. These drug-treated animals showed, similarly to experiments with a restrictive diet, a lower death rate, fewer glomerulopathies, and lower creatinine and protein levels in the serum. In addition, there were fewer tumour bearers, the total number of tumours was less, and the malignancy and formation of metastases was reduced. This experiment shows the importance which should be attached to the course of body weight gain during a long-term study. Only if these parameters are taken into consideration, an interpretation of the experimental results is possible.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0232-1513
pubmed:author
pubmed:issnType
Print
pubmed:volume
30
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
157-64
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1986
pubmed:articleTitle
Investigations on the exogenous influencing of the spontaneous tumour rate in rats.
pubmed:publicationType
Journal Article